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C1orf56 (NM_017860) Human Recombinant Protein

Product Specifications

Background

This gene is a proto-oncogene whose promoter is methylated by DNA methyltransferase 3B (DNMT3B), which represses the proto-oncogene. However, a catalytically inactive isoform of DNMT3B is overexpressed in lymphomas, leading to hypomethylation of the proto-oncogene's promoter and derepression of the proto-oncogene. [provided by RefSeq, Sep 2016]

Synonyms

MENT

Gene ID

54964

UniProt

Q9BUN1

Accession Number mRNA

NM_017860

Chromosomal Location

1q21.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

36.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

C1orf56

Species

Human

Protein ID

NP_060330

Overview

Recombinant protein of human chromosome 1 open reading frame 56 (C1orf56)

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/54964

Uniprot URL

https://www.uniprot.org/uniprot/Q9BUN1

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_017860

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_060330

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