C1orf56 (NM_017860) Human Recombinant Protein
Product Specifications
Background
This gene is a proto-oncogene whose promoter is methylated by DNA methyltransferase 3B (DNMT3B), which represses the proto-oncogene. However, a catalytically inactive isoform of DNMT3B is overexpressed in lymphomas, leading to hypomethylation of the proto-oncogene's promoter and derepression of the proto-oncogene. [provided by RefSeq, Sep 2016]
Overview
Recombinant protein of human chromosome 1 open reading frame 56 (C1orf56)
Synonyms
MENT
Gene ID
54964
UniProt
Q9BUN1
Accession Number mRNA
NM_017860
Chromosomal Location
1q21.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
36.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
C1orf56
Species
Human
Protein ID
NP_060330
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/54964
Uniprot URL
https://www.uniprot.org/uniprot/Q9BUN1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_017860
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_060330
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