FBXL12 (NM_017703) Human Recombinant Protein
Product Specifications
Background
Members of the F-box protein family, such as FBXL12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]) .[supplied by OMIM, Mar 2008]
Synonyms
Fbl12
Gene ID
54850
UniProt
Q9NXK8
Accession Number mRNA
NM_017703
Chromosomal Location
19p13.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
36.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
FBXL12
Species
Human
Protein ID
NP_060173
Overview
Recombinant protein of human F-box and leucine-rich repeat protein 12 (FBXL12)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/54850
Uniprot URL
https://www.uniprot.org/uniprot/Q9NXK8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_017703
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_060173
Curated Selection
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