TOLLIP (NM_019009) Human Recombinant Protein

Product Specifications

Background

This gene encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]

Overview

Recombinant protein of human toll interacting protein (TOLLIP)

Synonyms

IL-1RAcPIP

Gene ID

54472

UniProt

Q9H0E2, Q6FIE9

Accession Number mRNA

NM_019009

Chromosomal Location

11p15.5

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Toll-like receptor signaling pathway

Field of Research

Toll-like receptor signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

30.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.