Calnexin (CANX) (NM_001746) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER) -associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2018]
Overview
Recombinant protein of human calnexin (CANX), transcript variant 1
Synonyms
CNX; IP90; P90
Gene ID
821
UniProt
P27824
Accession Number mRNA
NM_001746
Chromosomal Location
5q35.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Antigen processing and presentation
Field of Research
Antigen processing and presentation
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
65.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CANX
Species
Human
Protein ID
NP_001737
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/821
Uniprot URL
https://www.uniprot.org/uniprot/P27824
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001746
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001737
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