UGP2 (NM_001001521) Human Recombinant Protein
Product Specifications
Background
The enzyme encoded by this gene is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue, UDP-glucose is a direct precursor of glycogen; in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. The eukaryotic enzyme has no significant sequence similarity to the prokaryotic enzyme. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
DEE83; EIEE83; pHC379; SVUGP2; UDPG; UDPGP; UDPGP2; UGP1; UGPP1; UGPP2
Gene ID
7360
UniProt
Q16851, A0A140VKE1
Accession Number mRNA
NM_001001521
Chromosomal Location
2p15
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Amino sugar and nucleotide sugar metabolism, Galactose metabolism, Metabolic pathways, Pentose and glucuronate interconversions, Starch and sucrose metabolism
Field of Research
Amino sugar and nucleotide sugar metabolism, Galactose metabolism, Metabolic pathways, Pentose and glucuronate interconversions, Starch and sucrose metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
55.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
UGP2
Species
Human
Protein ID
NP_001001521
Overview
Recombinant protein of human UDP-glucose pyrophosphorylase 2 (UGP2), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7360
Uniprot URL
https://www.uniprot.org/uniprot/Q16851
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001001521
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001001521
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