TIP30 (HTATIP2) (NM_006410) Human Recombinant Protein
Product Specifications
Background
Oxidoreductase required for tumor suppression. NAPDH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect.[UniProtKB/Swiss-Prot Function]
Synonyms
CC3; SDR44U1; TIP30
Gene ID
10553
UniProt
Q9BUP3
Accession Number mRNA
NM_006410
Chromosomal Location
11p15.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
26.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HTATIP2
Species
Human
Protein ID
NP_006401
Overview
Recombinant protein of human HIV-1 Tat interactive protein 2, 30kDa (HTATIP2), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10553
Uniprot URL
https://www.uniprot.org/uniprot/Q9BUP3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006410
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006401
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