S100A1 (NM_006271) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. [provided by RefSeq, Jul 2008]
Synonyms
S100; S100-alpha; S100A
Gene ID
6271
UniProt
P23297, A0A0S2Z4H2
Accession Number mRNA
NM_006271
Chromosomal Location
1q21.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
10.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
S100A1
Species
Human
Protein ID
NP_006262
Overview
Recombinant protein of human S100 calcium binding protein A1 (S100A1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6271
Uniprot URL
https://www.uniprot.org/uniprot/P23297
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006271
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006262
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