GPIP137 (CAPRIN1) (NM_005898) Human Recombinant Protein
Product Specifications
Background
May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human cell cycle associated protein 1 (CAPRIN1), transcript variant 1
Synonyms
GPIAP1; GPIP137; GRIP137; M11S1; p137GPI; RNG105
Gene ID
4076
UniProt
Q14444
Accession Number mRNA
NM_005898
Chromosomal Location
11p13
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Activity
25784705
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
78.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CAPRIN1
Species
Human
Protein ID
NP_005889
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4076
Uniprot URL
https://www.uniprot.org/uniprot/Q14444
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005898
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005889
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