CERT1 (NM_031361) Human Recombinant Protein
Product Specifications
Background
This gene encodes a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
CERT; CERTL; COL4A3BP; GPBP; MRD34; STARD11
Gene ID
10087
UniProt
Q9Y5P4, A0A024RAJ5
Accession Number mRNA
NM_031361
Chromosomal Location
5q13.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
67.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CERT1
Species
Human
Protein ID
NP_112729
Overview
Recombinant protein of human collagen, type IV, alpha 3 (Goodpasture antigen) binding protein (COL4A3BP), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10087
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y5P4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_031361
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_112729
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