Syntaxin 4 (STX4) (NM_004604) Human Recombinant Protein
Product Specifications
Background
Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity) . May also play a role in docking of synaptic vesicles at presynaptic active zones.[UniProtKB/Swiss-Prot Function]
Synonyms
P35-2; STX4A
Gene ID
6810
UniProt
Q12846
Accession Number mRNA
NM_004604
Chromosomal Location
16p11.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
SNARE interactions in vesicular transport
Field of Research
SNARE interactions in vesicular transport
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
34 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
STX4
Species
Human
Protein ID
NP_004595
Overview
Recombinant protein of human syntaxin 4 (STX4)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6810
Uniprot URL
https://www.uniprot.org/uniprot/Q12846
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004604
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004595
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