Syntaxin 4 (STX4) (NM_004604) Human Recombinant Protein

Product Specifications

Background

Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity) . May also play a role in docking of synaptic vesicles at presynaptic active zones.[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human syntaxin 4 (STX4)

Synonyms

P35-2; STX4A

Gene ID

6810

UniProt

Q12846

Accession Number mRNA

NM_004604

Chromosomal Location

16p11.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

SNARE interactions in vesicular transport

Field of Research

SNARE interactions in vesicular transport

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Transmembrane

Molecular Weight

34 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.