PAFAH2 (NM_000437) Human Recombinant Protein

Product Specifications

Background

This gene encodes platelet-activating factor acetylhydrolase isoform 2, a single-subunit intracellular enzyme that catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine) . However, this lipase exhibits a broader substrate specificity than simply platelet activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist, and both are multi-subunit enzymes. Additionally, there is a single-subunit serum isoform of this enzyme. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human platelet-activating factor acetylhydrolase 2, 40kDa (PAFAH2)

Synonyms

HSD-PLA2

Gene ID

5051

UniProt

Q99487

Accession Number mRNA

NM_000437

Chromosomal Location

1p36.11

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Ether lipid metabolism, Metabolic pathways

Field of Research

Ether lipid metabolism, Metabolic pathways

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

43.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.