PRPF4 (NM_004697) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is part of a heteromeric complex that binds U4, U5, and U6 small nuclear RNAs and is involved in pre-mRNA splicing. The encoded protein also is a mitotic checkpoint protein and a regulator of chemoresistance in human ovarian cancer. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2016]
Synonyms
HPRP4; HPRP4P; PRP4; Prp4p; RP70; SNRNP60
Gene ID
9128
UniProt
O43172
Accession Number mRNA
NM_004697
Chromosomal Location
9q32
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Spliceosome
Field of Research
Spliceosome
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
58.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PRPF4
Species
Human
Protein ID
NP_004688
Overview
Recombinant protein of human PRP4 pre-mRNA processing factor 4 homolog (yeast) (PRPF4)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9128
Uniprot URL
https://www.uniprot.org/uniprot/O43172
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004697
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004688
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