ECHS1 (NM_004092) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene functions in the second step of the mitochondrial fatty acid beta-oxidation pathway. It catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs. The gene product is a member of the hydratase/isomerase superfamily. It localizes to the mitochondrial matrix. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human enoyl Coenzyme A hydratase, short chain, 1, mitochondrial (ECHS1), nuclear gene encoding mitochondrial protein
Synonyms
ECHS1D; SCEH
Gene ID
1892
UniProt
P30084
Accession Number mRNA
NM_004092
Chromosomal Location
10q26.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Beta-Alanine metabolism, Butanoate metabolism, Fatty acid elongation in mitochondria, Fatty acid metabolism, Limonene and pinene degradation, Lysine degradation, Metabolic pathways, Propanoate metabolism, Tryptophan metabolism, Valine, leucine and isoleucine degradation
Field of Research
Beta-Alanine metabolism, Butanoate metabolism, Fatty acid elongation in mitochondria, Fatty acid metabolism, Limonene and pinene degradation, Lysine degradation, Metabolic pathways, Propanoate metabolism, Tryptophan metabolism, Valine, leucine and isoleucine degradation
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
31.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ECHS1
Species
Human
Protein ID
NP_004083
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1892
Uniprot URL
https://www.uniprot.org/uniprot/P30084
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004092
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004083
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