UROS (NM_000375) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene catalyzes the fourth step of porphyrin biosynthesis in the heme biosynthetic pathway. Defects in this gene cause congenital erythropoietic porphyria (Gunther's disease) . [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human uroporphyrinogen III synthase (UROS)

Synonyms

UROIIIS

Gene ID

7390

UniProt

P10746, A0A0S2Z4T8

Accession Number mRNA

NM_000375

Chromosomal Location

10q26.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Metabolic pathways, Porphyrin and chlorophyll metabolism

Field of Research

Metabolic pathways, Porphyrin and chlorophyll metabolism

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

28.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.