UROS (NM_000375) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene catalyzes the fourth step of porphyrin biosynthesis in the heme biosynthetic pathway. Defects in this gene cause congenital erythropoietic porphyria (Gunther's disease) . [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human uroporphyrinogen III synthase (UROS)
Synonyms
UROIIIS
Gene ID
7390
UniProt
P10746, A0A0S2Z4T8
Accession Number mRNA
NM_000375
Chromosomal Location
10q26.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Metabolic pathways, Porphyrin and chlorophyll metabolism
Field of Research
Metabolic pathways, Porphyrin and chlorophyll metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
28.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
UROS
Species
Human
Protein ID
NP_000366
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7390
Uniprot URL
https://www.uniprot.org/uniprot/P10746
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_000375
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_000366
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