14-3-3 beta (YWHAB) (NM_139323) Human Recombinant Protein

Product Specifications

Background

This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide (YWHAB), transcript variant 2

Synonyms

GW128; HEL-S-1; HS1; KCIP-1; YWHAA

Gene ID

7529

UniProt

P31946, V9HWD6

Accession Number mRNA

NM_139323

Chromosomal Location

20q13.12

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Cell cycle, Neurotrophin signaling pathway, Oocyte meiosis

Field of Research

Cell cycle, Neurotrophin signaling pathway, Oocyte meiosis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

27.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.