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UBE2G2 (NM_003343) Human Recombinant Protein

Product Specifications

Background

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse counterpart. This gene is ubiquitously expressed, with high expression seen in adult muscle. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

Synonyms

UBC7

Gene ID

7327

UniProt

P60604

Accession Number mRNA

NM_003343

Chromosomal Location

21q22.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Parkinson's disease, Ubiquitin mediated proteolysis

Field of Research

Parkinson's disease, Ubiquitin mediated proteolysis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

18.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

UBE2G2

Species

Human

Protein ID

NP_003334

Overview

Recombinant protein of human ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast) (UBE2G2), transcript variant 1

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/7327

Uniprot URL

https://www.uniprot.org/uniprot/P60604

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_003343

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_003334

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