What is the catalog number for SYK (NM_003177) Human Recombinant Protein?

The catalog number for SYK (NM_003177) Human Recombinant Protein is PH42044M5.

What sizes are available for SYK (NM_003177) Human Recombinant Protein?

SYK (NM_003177) Human Recombinant Protein is available in the following size(s): 20 µg.

Is SYK (NM_003177) Human Recombinant Protein in stock?

SYK (NM_003177) Human Recombinant Protein is currently made to order / not held in immediate stock. Contact us for lead time.

SYK (NM_003177) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

Overview

Recombinant protein of human spleen tyrosine kinase (SYK), transcript variant 1

Synonyms

IMD82; p72-Syk

Gene ID

6850

UniProt

P43405, A0A024R244

Accession Number mRNA

NM_003177

Chromosomal Location

9q22.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Natural killer cell mediated cytotoxicity

Field of Research

B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Natural killer cell mediated cytotoxicity

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Protein Kinase

Molecular Weight

71.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.