PPM1G (NM_002707) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. [provided by RefSeq, Apr 2010]
Synonyms
MGC1675; MGC2870; PP2CG; PP2CGAMMA; PPP2CG
Gene ID
5496
UniProt
O15355
Accession Number mRNA
NM_002707
Chromosomal Location
2p23.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Phosphatase
Molecular Weight
59.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PPM1G
Species
Human
Protein ID
NP_002698
Overview
Recombinant protein of human protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform (PPM1G), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5496
Uniprot URL
https://www.uniprot.org/uniprot/O15355
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002707
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002698
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