What is the catalog number for OGDH (NM_002541) Human Recombinant Protein?

The catalog number for OGDH (NM_002541) Human Recombinant Protein is PH42023M5.

What sizes are available for OGDH (NM_002541) Human Recombinant Protein?

OGDH (NM_002541) Human Recombinant Protein is available in the following size(s): 20 µg.

Is OGDH (NM_002541) Human Recombinant Protein in stock?

OGDH (NM_002541) Human Recombinant Protein is currently made to order / not held in immediate stock. Contact us for lead time.

OGDH (NM_002541) Human Recombinant Protein

Product Specifications

Background

This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO (2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009]

Overview

Recombinant protein of human oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) (OGDH), nuclear gene encoding mitochondrial protein, transcript variant 1

Synonyms

AKGDH; E1k; KGD1; OGDC; OGDH2

Gene ID

4967

UniProt

Q02218, B4E3E9

Accession Number mRNA

NM_002541

Chromosomal Location

7p13

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Citrate cycle (TCA cycle), Lysine degradation, Metabolic pathways, Tryptophan metabolism

Field of Research

Citrate cycle (TCA cycle), Lysine degradation, Metabolic pathways, Tryptophan metabolism

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

111.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.