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ICAM2 (NM_000873) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human intercellular adhesion molecule 2 (ICAM2), transcript variant 5

Synonyms

CD102

Gene ID

3384

UniProt

P13598, Q6FHE2

Accession Number mRNA

NM_000873

Chromosomal Location

17q23.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Cell adhesion molecules (CAMs), Natural killer cell mediated cytotoxicity

Field of Research

Cell adhesion molecules (CAMs), Natural killer cell mediated cytotoxicity

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

ES Cell Differentiation/IPS, Transmembrane

Molecular Weight

28.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

ICAM2

Species

Human

Protein ID

NP_000864

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/3384

Uniprot URL

https://www.uniprot.org/uniprot/P13598

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_000873

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_000864

Frequently Asked Questions

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