PRMT2 (NM_206962) Human Recombinant Protein
Product Specifications
Background
Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR) -mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER) -mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1-dependent manner) . May be involved in growth regulation.[UniProtKB/Swiss-Prot Function]
Synonyms
HRMT1L1
Gene ID
3275
UniProt
P55345, A0A0S2Z3N3
Accession Number mRNA
NM_206962
Chromosomal Location
21q22.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
48.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PRMT2
Species
Human
Protein ID
NP_996845
Overview
Recombinant protein of human protein arginine methyltransferase 2 (PRMT2), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3275
Uniprot URL
https://www.uniprot.org/uniprot/P55345
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_206962
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_996845
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