Heme Oxygenase 1 (HMOX1) (NM_002133) Human Recombinant Protein

Product Specifications

Background

Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human heme oxygenase (decycling) 1 (HMOX1)

Synonyms

BK286B10; HMOX1D; HO-1; HSP32

Gene ID

3162

UniProt

P09601, Q6FH11

Accession Number mRNA

NM_002133

Chromosomal Location

22q12.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Porphyrin and chlorophyll metabolism

Field of Research

Porphyrin and chlorophyll metabolism

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Transmembrane

Molecular Weight

32.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.