Heme Oxygenase 1 (HMOX1) (NM_002133) Human Recombinant Protein
Product Specifications
Background
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. [provided by RefSeq, Jul 2008]
Synonyms
BK286B10; HMOX1D; HO-1; HSP32
Gene ID
3162
UniProt
P09601, Q6FH11
Accession Number mRNA
NM_002133
Chromosomal Location
22q12.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Porphyrin and chlorophyll metabolism
Field of Research
Porphyrin and chlorophyll metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
32.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HMOX1
Species
Human
Protein ID
NP_002124
Overview
Recombinant protein of human heme oxygenase (decycling) 1 (HMOX1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3162
Uniprot URL
https://www.uniprot.org/uniprot/P09601
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002133
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002124
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