What is the catalog number for GMDS (NM_001500) Human Recombinant Protein?

The catalog number for GMDS (NM_001500) Human Recombinant Protein is PH42006M5.

What sizes are available for GMDS (NM_001500) Human Recombinant Protein?

GMDS (NM_001500) Human Recombinant Protein is available in the following size(s): 20 µg.

Is GMDS (NM_001500) Human Recombinant Protein in stock?

GMDS (NM_001500) Human Recombinant Protein is currently made to order / not held in immediate stock. Contact us for lead time.

GMDS (NM_001500) Human Recombinant Protein

Product Specifications

Background

GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020) .[supplied by OMIM, Aug 2009]

Overview

Recombinant protein of human GDP-mannose 4, 6-dehydratase (GMDS)

Synonyms

GMD; SDR3E1

Gene ID

2762

UniProt

O60547, E9PI88

Accession Number mRNA

NM_001500

Chromosomal Location

6p25.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism, Metabolic pathways

Field of Research

Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism, Metabolic pathways

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

41.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.