FOXO1 (NM_002015) Human Recombinant Protein
Product Specifications
Background
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human forkhead box O1 (FOXO1)
Synonyms
FKH1; FKHR; FOXO1A
Gene ID
2308
UniProt
Q12778
Accession Number mRNA
NM_002015
Chromosomal Location
13q14.11
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Insulin signaling pathway, Pathways in cancer, Prostate cancer
Field of Research
Insulin signaling pathway, Pathways in cancer, Prostate cancer
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Activity
29066835
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transcription Factors
Molecular Weight
69.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
FOXO1
Species
Human
Protein ID
NP_002006
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2308
Uniprot URL
https://www.uniprot.org/uniprot/Q12778
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002015
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002006
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