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Actin Regulatory Protein CAPG (CAPG) (NM_001747) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2012]

Overview

Recombinant protein of human capping protein (actin filament), gelsolin-like (CAPG)

Synonyms

AFCP; HEL-S-66; MCP

Gene ID

822

UniProt

P40121, V9HW69

Accession Number mRNA

NM_001747

Chromosomal Location

2p11.2

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

38.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

CAPG

Species

Human

Protein ID

NP_001738

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/822

Uniprot URL

https://www.uniprot.org/uniprot/P40121

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001747

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001738

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