P70 S6 Kinase beta (RPS6KB2) (NM_003952) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B) . Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation. [provided by RefSeq, Jan 2015]
Overview
Recombinant protein of human ribosomal protein S6 kinase, 70kDa, polypeptide 2 (RPS6KB2)
Synonyms
KLS; p70 (S6K) -beta; P70-beta; P70-beta-1; P70-beta-2; p70S6Kb; S6K-beta2; S6K2; S6KB; S6Kbeta; S6KI (2) ; SRK; STK14B
Gene ID
6199
UniProt
Q9UBS0
Accession Number mRNA
NM_003952
Chromosomal Location
11q13.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Acute myeloid leukemia, ErbB signaling pathway, Fc gamma R-mediated phagocytosis, Insulin signaling pathway, mTOR signaling pathway, TGF-beta signaling pathway
Field of Research
Acute myeloid leukemia, ErbB signaling pathway, Fc gamma R-mediated phagocytosis, Insulin signaling pathway, mTOR signaling pathway, TGF-beta signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protein Kinase
Molecular Weight
53.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
RPS6KB2
Species
Human
Protein ID
NP_003943
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6199
Uniprot URL
https://www.uniprot.org/uniprot/Q9UBS0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003952
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003943
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC940831-500 1x 500 µL
Calponin-1 (CALP), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNCB1820-100 1x 100 µL
Ep-CAM / CD326 (Epithelial Marker) (rVU-1D9), Biotin conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC050968-500 1x 500 µL
CD63 (LAMP3/968), CF405M conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC401819-500 1x 500 µL
Ep-CAM / CD326 (Epithelial Marker) (rMOC-31), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC470017-100 1x 100 µL
Ep-CAM / CD326 (VU-1D9), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details