UROD (NM_000374) Human Recombinant Protein
Product Specifications
Background
This gene encodes an enzyme in the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria.[provided by RefSeq, Aug 2010]
Synonyms
PCT; UPD
Gene ID
7389
UniProt
P06132
Accession Number mRNA
NM_000374
Chromosomal Location
1p34.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Porphyrin and chlorophyll metabolism
Field of Research
Porphyrin and chlorophyll metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
40.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
UROD
Species
Human
Protein ID
NP_000365
Overview
Recombinant protein of human uroporphyrinogen decarboxylase (UROD)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7389
Uniprot URL
https://www.uniprot.org/uniprot/P06132
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_000374
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_000365
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