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H2AZ2 (NM_012412) Human Recombinant Protein

Product Specifications

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. Several transcript variants encoding different isoforms, have been identified for this gene. [provided by RefSeq, Oct 2015]

Overview

Recombinant protein of human H2A histone family, member V (H2AFV), transcript variant 1

Synonyms

H2A.Z-2; H2AFV; H2AV

Gene ID

94239

UniProt

Q71UI9

Accession Number mRNA

NM_012412

Chromosomal Location

7p13

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Systemic lupus erythematosus

Field of Research

Systemic lupus erythematosus

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

13.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

H2AZ2

Species

Human

Protein ID

NP_036544

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/94239

Uniprot URL

https://www.uniprot.org/uniprot/Q71UI9

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_012412

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_036544

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