H2AZ2 (NM_012412) Human Recombinant Protein
Product Specifications
Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. Several transcript variants encoding different isoforms, have been identified for this gene. [provided by RefSeq, Oct 2015]
Overview
Recombinant protein of human H2A histone family, member V (H2AFV), transcript variant 1
Synonyms
H2A.Z-2; H2AFV; H2AV
Gene ID
94239
UniProt
Q71UI9
Accession Number mRNA
NM_012412
Chromosomal Location
7p13
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Systemic lupus erythematosus
Field of Research
Systemic lupus erythematosus
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
13.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
H2AZ2
Species
Human
Protein ID
NP_036544
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/94239
Uniprot URL
https://www.uniprot.org/uniprot/Q71UI9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_012412
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_036544
Frequently Asked Questions
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