STK16 (NM_003691) Human Recombinant Protein
Selected Variant
PH41946M5
Size: 20 µg
Product Specifications
Background
Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins.[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human serine/threonine kinase 16 (STK16), transcript variant 1
Synonyms
FLJ39635; KRCT; KRCT, MPSK, TSF1, PKL12, FLJ39635; MPSK; PKL12; protein kinase expressed in day 12 fetal liver; serine/threonine kinase 16; TSF1
Gene ID
8576
UniProt
O75716
Accession Number mRNA
NM_003691
Chromosomal Location
2q35
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protein Kinase
Molecular Weight
35.1
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
STK16
Species
Human
Protein ID
NP_003682
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8576
Uniprot URL
https://www.uniprot.org/uniprot/O75716
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003691
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003682
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