GNG5 (NM_005274) Human Recombinant Protein
Product Specifications
Background
G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors. Interaction of a G protein with its activated receptor promotes exchange of GTP for GDP that is bound to the alpha subunit. The alpha-GTP complex dissociates from the beta-gamma heterodimer so that the subunits, in turn, may interact with and regulate effector molecules (Gilman, 1987 [PubMed 3113327]; summary by Ahmad et al., 1995) [PubMed 7606925].[supplied by OMIM, Nov 2010]
Overview
Recombinant protein of human guanine nucleotide binding protein (G protein), gamma 5 (GNG5)
Synonyms
FLJ92393
Gene ID
2787
UniProt
P63218
Accession Number mRNA
NM_005274
Chromosomal Location
1p22.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Chemokine signaling pathway
Field of Research
Chemokine signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
7.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GNG5
Species
Human
Protein ID
NP_005265
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2787
Uniprot URL
https://www.uniprot.org/uniprot/P63218
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005274
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005265
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