GNG5 (NM_005274) Human Recombinant Protein

Product Specifications

Background

G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors. Interaction of a G protein with its activated receptor promotes exchange of GTP for GDP that is bound to the alpha subunit. The alpha-GTP complex dissociates from the beta-gamma heterodimer so that the subunits, in turn, may interact with and regulate effector molecules (Gilman, 1987 [PubMed 3113327]; summary by Ahmad et al., 1995) [PubMed 7606925].[supplied by OMIM, Nov 2010]

Overview

Recombinant protein of human guanine nucleotide binding protein (G protein), gamma 5 (GNG5)

Synonyms

FLJ92393

Gene ID

2787

UniProt

P63218

Accession Number mRNA

NM_005274

Chromosomal Location

1p22.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Chemokine signaling pathway

Field of Research

Chemokine signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

7.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.