KDM4A (NM_014663) Human Recombinant Protein
Product Specifications
Background
This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. [provided by RefSeq, Apr 2009]
Synonyms
JHDM3A; JMJD2; JMJD2A; TDRD14A
Gene ID
9682
UniProt
O75164
Accession Number mRNA
NM_014663
Chromosomal Location
1p34.2-p34.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transcription Factors
Molecular Weight
120.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
KDM4A
Species
Human
Protein ID
NP_055478
Overview
Recombinant protein of human jumonji domain containing 2A (JMJD2A)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9682
Uniprot URL
https://www.uniprot.org/uniprot/O75164
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_014663
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_055478
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