NMT1 (NM_021079) Human Recombinant Protein
Product Specifications
Background
Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase (NMT; EC 2.3.1.97) catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1; MIM 139311) (Duronio et al., 1992 [PubMed 1570339]) .[supplied by OMIM, Nov 2008]
Synonyms
NMT
Gene ID
4836
UniProt
P30419
Accession Number mRNA
NM_021079
Chromosomal Location
17q21.31
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
56.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NMT1
Species
Human
Protein ID
NP_066565
Overview
Recombinant protein of human N-myristoyltransferase 1 (NMT1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4836
Uniprot URL
https://www.uniprot.org/uniprot/P30419
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_021079
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_066565
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