HGS (NM_004712) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. [provided by RefSeq, Dec 2010]
Overview
Recombinant protein of human hepatocyte growth factor-regulated tyrosine kinase substrate (HGS)
Synonyms
HRS
Gene ID
9146
UniProt
O14964, A0A0S2Z4R4
Accession Number mRNA
NM_004712
Chromosomal Location
17q25.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Endocytosis
Field of Research
Endocytosis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
86 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HGS
Species
Human
Protein ID
NP_004703
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9146
Uniprot URL
https://www.uniprot.org/uniprot/O14964
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004712
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004703
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