Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

FH (NM_000143) Human Recombinant Protein

Selected Variant

PH41919M5

Size: 20 µg

Product Specifications

Background

The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human fumarate hydratase (FH), nuclear gene encoding mitochondrial protein

Synonyms

FMRD; HLRCC; HsFH; LRCC; MCL; MCUL1

Gene ID

2271

UniProt

P07954, A0A0S2Z4C3

Accession Number mRNA

NM_000143

Chromosomal Location

1q43

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Citrate cycle (TCA cycle), Metabolic pathways, Pathways in cancer, Renal cell carcinoma

Field of Research

Citrate cycle (TCA cycle), Metabolic pathways, Pathways in cancer, Renal cell carcinoma

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

50.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

FH

Species

Human

Protein ID

NP_000134

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2271

Uniprot URL

https://www.uniprot.org/uniprot/P07954

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_000143

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_000134

Price

Sign In for Pricing

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Anti-NQO1 Antibody Picoband® (APC Conjugate)
PB9497-APC 100 µg/Vial

Anti-NQO1 Antibody Picoband® (APC Conjugate)

Sign In for Pricing
View Details
SATB2 Recombinant Rabbit Monoclonal Antibody [PD01-42]
HA721223 100 µL

SATB2 Recombinant Rabbit Monoclonal Antibody [PD01-42]

Sign In for Pricing
View Details
CD3e (T-Cell Marker) (rC3e/1308), CF568 conjugate, 0.1mg/mL
BNC683631-100 1x 100 µL

CD3e (T-Cell Marker) (rC3e/1308), CF568 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/11), CF405S conjugate, 0.1mg/mL
BNC040011-500 1x 500 µL

P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/11), CF405S conjugate, 0.1mg/mL

Sign In for Pricing
View Details
PGP9.5 / UchL1 (pan-Neuronal Marker) (rUCHL1/775), CF640R conjugate, 0.1mg/mL
BNC402205-500 1x 500 µL

PGP9.5 / UchL1 (pan-Neuronal Marker) (rUCHL1/775), CF640R conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Anti-Cullin 4B/CUL4B Antibody Picoband®, APC Conjugate
PA1233-APC 100 µg/Vial

Anti-Cullin 4B/CUL4B Antibody Picoband®, APC Conjugate

Sign In for Pricing
View Details