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Spermine synthase (SMS) (NM_004595) Human Recombinant Protein

Product Specifications

Background

This gene encodes a protein belonging to the spermidine/spermin synthase family and catalyzes the production of spermine from spermidine. Pseudogenes of this gene are located on chromosomes 1, 5, 6 and X. Mutations in this gene cause an X-linked intellectual disability called Snyder-Robinson Syndrome (SRS) . Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]

Synonyms

MRSR; SPMSY; SpS; SRS

Gene ID

6611

UniProt

P52788

Accession Number mRNA

NM_004595

Chromosomal Location

Xp22.11

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Arginine and proline metabolism, beta-Alanine metabolism, Cysteine and methionine metabolism, Glutathione metabolism, Metabolic pathways

Field of Research

Arginine and proline metabolism, beta-Alanine metabolism, Cysteine and methionine metabolism, Glutathione metabolism, Metabolic pathways

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

41.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

SMS

Species

Human

Protein ID

NP_004586

Overview

Recombinant protein of human spermine synthase (SMS)

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/6611

Uniprot URL

https://www.uniprot.org/uniprot/P52788

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004595

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_004586

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