ADK (NM_001123) Human Recombinant Protein
Product Specifications
Background
This gene an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
Overview
Purified recombinant protein of Homo sapiens adenosine kinase (ADK), transcript variant ADK-short
Synonyms
AK
Gene ID
132
UniProt
P55263, A0A140VJE0
Accession Number mRNA
NM_001123
Chromosomal Location
10q22.2|10q11-q24
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Metabolic pathways, Purine metabolism
Field of Research
Metabolic pathways, Purine metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
38.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ADK
Species
Human
Protein ID
NP_001114
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/132
Uniprot URL
https://www.uniprot.org/uniprot/P55263
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001123
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001114
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