ICAM4 (NM_001039132) Human Recombinant Protein
Product Specifications
Background
This gene encodes the Landsteiner-Wiener (LW) blood group antigen (s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW (A) /LW (B) blood group antigens is a single aa variation at position 100; Gln-100=LW (A) and Arg-100=LW (B) . Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Synonyms
CD242; LW
Gene ID
3386
UniProt
Q14773, U5U6P8
Accession Number mRNA
NM_001039132
Chromosomal Location
19p13.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Secreted Protein, Transmembrane
Molecular Weight
27.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ICAM4
Species
Human
Protein ID
NP_001034221
Overview
Recombinant protein of human intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) (ICAM4), transcript variant 3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3386
Uniprot URL
https://www.uniprot.org/uniprot/Q14773
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001039132
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001034221
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
