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POLR2H (NM_006232) Human Recombinant Protein

Selected Variant

PH41897M5

Size: 20 µg

Product Specifications

Background

The three eukaryotic RNA polymerases are complex multisubunit enzymes that play a central role in the transcription of nuclear genes. This gene encodes an essential and highly conserved subunit of RNA polymerase II that is shared by the other two eukaryotic DNA-directed RNA polymerases, I and III. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]

Overview

Recombinant protein of human polymerase (RNA) II (DNA directed) polypeptide H (POLR2H)

Synonyms

RPABC3; RPB8; RPB17

Gene ID

5437

UniProt

P52434

Accession Number mRNA

NM_006232

Chromosomal Location

3q27.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Huntington's disease, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, RNA polymerase

Field of Research

Huntington's disease, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, RNA polymerase

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transcription Factors

Molecular Weight

17 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

POLR2H

Species

Human

Protein ID

NP_006223

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/5437

Uniprot URL

https://www.uniprot.org/uniprot/P52434

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_006232

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_006223

Price

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