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FKBP1B (NM_054033) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq, Jul 2008]

Synonyms

FKBP1L; FKBP12.6; OTK4; PKBP1L; PPIase

Gene ID

2281

UniProt

P68106

Accession Number mRNA

NM_054033

Chromosomal Location

2p23.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

8.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

FKBP1B

Species

Human

Protein ID

NP_473374

Overview

Recombinant protein of human FK506 binding protein 1B, 12.6 kDa (FKBP1B), transcript variant 2

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2281

Uniprot URL

https://www.uniprot.org/uniprot/P68106

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_054033

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_473374

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