DDOST (NM_005216) Human Recombinant Protein
Product Specifications
Background
This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia. [provided by RefSeq, Jul 2008]
Synonyms
AGER1; CDG1R; GATD6; OKSWcl45; OST; OST48; WBP1
Gene ID
1650
UniProt
P39656, A0A024RAD5
Accession Number mRNA
NM_005216
Chromosomal Location
1p36.12
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Metabolic pathways, N-Glycan biosynthesis
Field of Research
Metabolic pathways, N-Glycan biosynthesis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
46.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DDOST
Species
Human
Protein ID
NP_005207
Overview
Recombinant protein of human dolichyl-diphosphooligosaccharide-protein glycosyltransferase (DDOST)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1650
Uniprot URL
https://www.uniprot.org/uniprot/P39656
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005216
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005207
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