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TCP1 alpha (TCP1) (NM_030752) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, three pseudogenes that appear to be derived from this gene have been found. [provided by RefSeq, Jun 2010]

Synonyms

CCT-alpha; CCT1; CCTa; D6S230E; TCP-1-alpha

Gene ID

6950

UniProt

P17987

Accession Number mRNA

NM_030752

Chromosomal Location

6q25.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

60.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

TCP1

Species

Human

Protein ID

NP_110379

Overview

Recombinant protein of human t-complex 1 (TCP1), transcript variant 1

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/6950

Uniprot URL

https://www.uniprot.org/uniprot/P17987

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_030752

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_110379

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