TCP1 alpha (TCP1) (NM_030752) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, three pseudogenes that appear to be derived from this gene have been found. [provided by RefSeq, Jun 2010]
Synonyms
CCT-alpha; CCT1; CCTa; D6S230E; TCP-1-alpha
Gene ID
6950
UniProt
P17987
Accession Number mRNA
NM_030752
Chromosomal Location
6q25.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
60.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TCP1
Species
Human
Protein ID
NP_110379
Overview
Recombinant protein of human t-complex 1 (TCP1), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6950
Uniprot URL
https://www.uniprot.org/uniprot/P17987
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_030752
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_110379
Curated Selection
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