FLI1 (NM_002017) Human Recombinant Protein
Product Specifications
Background
This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t (11;22) (q24; q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t (4;11) (q21; q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Synonyms
BDPLT21; EWSR2; SIC-1
Gene ID
2313
UniProt
Q01543, A0A024R3M5
Accession Number mRNA
NM_002017
Chromosomal Location
11q24.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transcription Factors
Molecular Weight
50.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
FLI1
Species
Human
Protein ID
NP_002008
Overview
Recombinant protein of human Friend leukemia virus integration 1 (FLI1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2313
Uniprot URL
https://www.uniprot.org/uniprot/Q01543
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002017
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002008
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