NAGA (NM_000262) Human Recombinant Protein

Product Specifications

Background

NAGA encodes the lysosomal enzyme alpha-N-acetylgalactosaminidase, which cleaves alpha-N-acetylgalactosaminyl moieties from glycoconjugates. Mutations in NAGA have been identified as the cause of Schindler disease types I and II (type II also known as Kanzaki disease) . [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human N-acetylgalactosaminidase, alpha- (NAGA)

Synonyms

D22S674; GALB

Gene ID

4668

UniProt

P17050, A0A024R1Q5

Accession Number mRNA

NM_000262

Chromosomal Location

22q13.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Glycosphingolipid biosynthesis - globo series, Lysosome

Field of Research

Glycosphingolipid biosynthesis - globo series, Lysosome

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

44.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.