RRM1 (NM_001033) Human Recombinant Protein
Product Specifications
Background
This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Overview
Recombinant protein of human ribonucleotide reductase M1 (RRM1)
Synonyms
R1; RIR1; RR1
Gene ID
6240
UniProt
P23921
Accession Number mRNA
NM_001033
Chromosomal Location
11p15.4
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism
Field of Research
Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Activity
29765556
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
89.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
RRM1
Species
Human
Protein ID
NP_001024
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6240
Uniprot URL
https://www.uniprot.org/uniprot/P23921
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001033
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001024
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
133766 100 µL
SPHK1 (Sphingosine Kinase 1, SK 1, SPHK, SPK 1, SPK) (Not for Export EU)
Sign In for Pricing
View Details