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Lysozyme (LYZ) (NM_000239) Human Recombinant Protein

Product Specifications

Background

This gene encodes human lysozyme, whose natural substrate is the bacterial cell wall peptidoglycan (cleaving the beta[1-4]glycosidic linkages between N-acetylmuramic acid and N-acetylglucosamine) . Lysozyme is one of the antimicrobial agents found in human milk, and is also present in spleen, lung, kidney, white blood cells, plasma, saliva, and tears. The protein has antibacterial activity against a number of bacterial species. Missense mutations in this gene have been identified in heritable renal amyloidosis. [provided by RefSeq, Oct 2014]

Overview

Recombinant protein of human lysozyme (renal amyloidosis) (LYZ)

Synonyms

LYZF1; LZM

Gene ID

4069

UniProt

P61626, B2R4C5

Accession Number mRNA

NM_000239

Chromosomal Location

12q15

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

14.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

LYZ

Species

Human

Protein ID

NP_000230

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/4069

Uniprot URL

https://www.uniprot.org/uniprot/P61626

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_000239

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_000230

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