Integrin beta 5 (ITGB5) (NM_002213) Human Recombinant Protein
Product Specifications
Background
This gene encodes a beta subunit of integrin, which can combine with different alpha chains to form a variety of integrin heterodimers. Integrins are integral cell-surface receptors that participate in cell adhesion as well as cell-surface mediated signaling. The alphav beta5 integrin is involved in adhesion to vitronectin. [provided by RefSeq, Aug 2017]
Synonyms
FLJ26658
Gene ID
3693
UniProt
P18084, L7RT22
Accession Number mRNA
NM_002213
Chromosomal Location
3q21.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Regulation of actin cytoskeleton
Field of Research
Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Regulation of actin cytoskeleton
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
87.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ITGB5
Species
Human
Protein ID
NP_002204
Overview
Recombinant protein of human integrin, beta 5 (ITGB5)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3693
Uniprot URL
https://www.uniprot.org/uniprot/P18084
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002213
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002204
Curated Selection
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