ACTR1A (NM_005736) Human Recombinant Protein
Product Specifications
Background
This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin. [provided by RefSeq, Jul 2008]
Synonyms
ARP1; Arp1A; CTRN1
Gene ID
10121
UniProt
P61163, A0A384NQ21
Accession Number mRNA
NM_005736
Chromosomal Location
10q24.32
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
42.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ACTR1A
Species
Human
Protein ID
NP_005727
Overview
Recombinant protein of human ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) (ACTR1A)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10121
Uniprot URL
https://www.uniprot.org/uniprot/P61163
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005736
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005727
Curated Selection
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