MAD3 (MXD3) (NM_031300) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.[provided by RefSeq, Dec 2008]
Overview
Recombinant protein of human MAX dimerization protein 3 (MXD3), transcript variant 1
Synonyms
BHLHC13; MAD3; MYX
Gene ID
83463
UniProt
Q9BW11, A0A024R7S0
Accession Number mRNA
NM_031300
Chromosomal Location
5q35.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transcription Factors
Molecular Weight
23.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MXD3
Species
Human
Protein ID
NP_112590
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/83463
Uniprot URL
https://www.uniprot.org/uniprot/Q9BW11
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_031300
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_112590
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