L3MBTL2 (NM_031488) Human Recombinant Protein
Product Specifications
Background
Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.[UniProtKB/Swiss-Prot Function]
Synonyms
H-l (3) mbt-l; L3MBT
Gene ID
83746
UniProt
Q969R5, A0A0S2Z5X6
Accession Number mRNA
NM_031488
Chromosomal Location
22q13.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transcription Factors
Molecular Weight
78.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
L3MBTL2
Species
Human
Protein ID
NP_113676
Overview
Recombinant protein of human l (3) mbt-like 2 (Drosophila) (L3MBTL2)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/83746
Uniprot URL
https://www.uniprot.org/uniprot/Q969R5
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_031488
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_113676
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